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Wednesday 28 January 2015

TARGET THERAPY in Gallbladder Cancer treatment

Gallbladder treatment, chemotherapy has been found to show limited or very less results. Researchers are coming up with a new line of treatment , known as TARGET THERAPY. These drugs are used in combinations of chemotherapy  drugs are now being tested for people with gallbladder cancer.

TARGET THERAPIES

These kind of therapies, are usually drugs or substances that targets the specific molecules in cancer cell growth. In contrast to the chemotherapy drugs, who act against cell division to stop their growth.

These drugs are target oriented and target parts of cancerous cells or  around their neighboring environments. Many of these new drugs target cells with specific changes in gene(s).

One such target are the tumor blood vessels. Gallbladder tumor require the new blood vessels to grow beyond a certain size. Such target drugs are said to really effective especially  in the treatment of Gallbladder cancer. For instance  Bevacizumab (Avastin®) and pazopanib (Votrient®) are examples of drugs that target blood vessel growth and are being studied for their use against gallbladder cancer.

Many other drugs have different targets For example, a protein, EGFR found in high amounts on certain types of cancer cell, is said to be helping the cancer cells in their growth. Drugs such as lapatinib (Tykerb®) and cetuximab (Erbitux®), are now being studied for  their usage in patients with gallbladder cancer,  along with chemotherapy and other targeted drugs.

Drugs such as MEK inhibitors, selumetinib and such as trametinib (Mekinist®) and, are also being studied for their use in the treatment of gallbladder cancer.

Courtesy: www.cancer.org

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